4,5-dihydroxyphthalate decarboxylase

The enzyme 4,5-dihydroxyphthalate decarboxylase (EC 4.1.1.55) catalyzes the chemical reaction

4,5-dihydroxyphthalate ${\displaystyle \rightleftharpoons }$ 3,4-dihydroxybenzoate + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming). This enzyme is also called 4,5-dihydroxyphthalate carboxy-lyase. This enzyme participates in 2,4-dichlorobenzoate degradation.

References

• Ribbons DW, Evans WC (1966). "Oxidative metabolism of phthalic acid by soil pseudomonads". Biochem. J. 76: 310–318.