CTTNBP2NL

Protein-coding gene in the species Homo sapiens
CTTNBP2NL
Identifiers
AliasesCTTNBP2NL, CTTNBP2 N-terminal like
External IDsOMIM: 615100; MGI: 1933137; HomoloGene: 36371; GeneCards: CTTNBP2NL; OMA:CTTNBP2NL - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for CTTNBP2NL
Genomic location for CTTNBP2NL
Band1p13.2Start112,396,214 bp[1]
End112,463,456 bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for CTTNBP2NL
Genomic location for CTTNBP2NL
Band3|3 F2.2Start104,909,231 bp[2]
End104,960,462 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • skin of arm

  • amniotic fluid

  • pancreatic epithelial cell

  • sural nerve

  • skin of hip

  • skin of thigh

  • gums

  • gingival epithelium

  • visceral pleura
Top expressed in
  • endothelial cell of lymphatic vessel

  • trigeminal ganglion

  • sciatic nerve

  • secondary oocyte

  • zygote

  • left lung lobe

  • primary oocyte

  • stroma of bone marrow

  • primitive streak

  • fossa
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein phosphatase 2A binding
  • protein binding
Cellular component
  • cytoplasm
  • actin cytoskeleton
  • cytoskeleton
Biological process
  • protein dephosphorylation
  • negative regulation of transporter activity
  • negative regulation of transmembrane transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55917

80281

Ensembl

ENSG00000143079

ENSMUSG00000062127

UniProt

Q9P2B4

Q99LJ0

RefSeq (mRNA)

NM_018704

NM_001163332
NM_001163333
NM_030249

RefSeq (protein)

NP_061174

NP_001156804
NP_001156805
NP_084525

Location (UCSC)Chr 1: 112.4 – 112.46 MbChr 3: 104.91 – 104.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CTTNBP2 N-terminal-like protein is a protein that in humans is encoded by the CTTNBP2NL gene.[5][6] It is a substrate for phosphorylation.[7]

Interactions

CTTNBP2NL has been shown to interact with:

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000143079 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000062127 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Feb 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
  6. ^ "Entrez Gene: CTTNBP2NL CTTNBP2 N-terminal like".
  7. ^ a b c d e f g h i j Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.

External links

Further reading

  • Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
  • Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (Oct 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
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