Cefaloglycin
Chemical compound
- none
- (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2R)-2-amino-2-phenylacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 3577-01-3 Y
- 19150
- DB00689 Y
- 18069 Y
- HD2D469W6U
- D01949 Y
- CHEBI:34613 Y
- ChEMBL1200971 N
- DTXSID4022781
- Interactive image
- O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccccc3)N)COC(=O)C)C(=O)O
InChI
- InChI=1S/C18H19N3O6S/c1-9(22)27-7-11-8-28-17-13(16(24)21(17)14(11)18(25)26)20-15(23)12(19)10-5-3-2-4-6-10/h2-6,12-13,17H,7-8,19H2,1H3,(H,20,23)(H,25,26)/t12-,13-,17-/m1/s1 Y
- Key:FUBBGQLTSCSAON-PBFPGSCMSA-N Y
Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic.
References
- Tune B, Hsu C (1990). "The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem". J Am Soc Nephrol. 1 (5): 815–21. doi:10.1681/ASN.V15815. PMID 2133431.
- Tune B, Fravert D, Hsu C (1989). "Oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin". Biochem Pharmacol. 38 (5): 795–802. doi:10.1016/0006-2952(89)90233-5. PMID 2930580.
External links
- Media related to Cefaloglycin at Wikimedia Commons
- v
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(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases)
Glycopeptides Lipoglycopeptides |
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Lipopeptides |
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Polymyxins |
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Other |
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- Inhibit PG subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
- Hydrolyze NAM-NAG
- Tyrothricin
- Isoniazid#
- Teixobactin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it. |
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