Cloprostenol
Chemical compound
- QG02AD90 (WHO)
- (5Z)-7-{(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-5-heptenoic acid
- 40665-92-7
- 5311053
- 4470590
- 4208238832
- DTXSID50860575 DTXSID7048372, DTXSID50860575
- Interactive image
- c1cc(cc(c1)Cl)OC[C@@H](/C=C/[C@H]2[C@@H](C[C@@H]([C@@H]2C/C=C\CCCC(=O)O)O)O)O
InChI
- InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
- Key:VJGGHXVGBSZVMZ-QIZQQNKQSA-N
Cloprostenol is a synthetic analogue of prostaglandin F2α (PGF2α).[1] It is a potent luteolytic agent; this means that, within hours of administration, it causes the corpus luteum to stop production of progesterone, and to reduce in size over several days.[1] This effect is used in animals to induce estrus and to cause abortion.[2]
References
- ^ a b Cooper M (January 1981). "Prostaglandins in veterinary practice". In Practice. 3 (1): 30, 32–4. doi:10.1136/inpract.3.1.30. PMID 7346485. S2CID 6197103.
- ^ Plumb DC (2015). "Cloprostenol Sodium". Plumb's Veterinary Drug Handbook (8th ed.). Wiley. ISBN 9781118911938.
- v
- t
- e