GH1 |
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Available structures |
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PDB | Human UniProt search: PDBe RCSB |
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List of PDB id codes |
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1AXI, 1HUW, 1A22, 1HGU, 3HHR, 1KF9, 1HWG, 1BP3, 1HWH |
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Identifiers |
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Aliases | GH1, GH, GH-N, GHN, IGHD1B, hGH-N, GHB5, Growth hormone 1, IGHD2, IGHD1A |
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External IDs | OMIM: 139250 HomoloGene: 128036 GeneCards: GH1 |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17q23.3 | Start | 63,917,200 bp[1] |
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End | 63,918,839 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - pituitary gland
- anterior pituitary
- right coronary artery
- gastric mucosa
- right uterine tube
- canal of the cervix
- gastrocnemius muscle
- spleen
- left coronary artery
- body of pancreas
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| | More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - hormone activity
- metal ion binding
- protein binding
- growth factor activity
- growth hormone receptor binding
- prolactin receptor binding
| Cellular component | - extracellular region
- extracellular space
- endosome lumen
- growth hormone receptor complex
- collagen-containing extracellular matrix
| Biological process | - growth hormone receptor signaling pathway via JAK-STAT
- response to estradiol
- positive regulation of MAP kinase activity
- positive regulation of receptor internalization
- bone maturation
- growth hormone receptor signaling pathway
- positive regulation of insulin-like growth factor receptor signaling pathway
- positive regulation of multicellular organism growth
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of phosphatidylinositol 3-kinase signaling
- positive regulation of receptor signaling pathway via JAK-STAT
- positive regulation of activation of Janus kinase activity
- positive regulation of tyrosine phosphorylation of STAT protein
- regulation of signaling receptor activity
- positive regulation of glucose transmembrane transport
- response to nutrient levels
- positive regulation of growth
- animal organ development
- signal transduction
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_000515 NM_022559 NM_022560 NM_022561 NM_022562 |
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RefSeq (protein) | |
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NP_000506 NP_072053 NP_072054 |
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Location (UCSC) | Chr 17: 63.92 – 63.92 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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