MAP3K13 |
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Identifiers |
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Aliases | MAP3K13, LZK, MEKK13, MLK, mitogen-activated protein kinase kinase kinase 13 |
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External IDs | OMIM: 604915; MGI: 2444243; HomoloGene: 37958; GeneCards: MAP3K13; OMA:MAP3K13 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 3 (human)[1] |
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| Band | 3q27.2 | Start | 185,282,941 bp[1] |
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End | 185,489,094 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 16 (mouse)[2] |
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| Band | 16|16 B1 | Start | 21,613,096 bp[2] |
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End | 21,752,189 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - corpus epididymis
- caput epididymis
- sperm
- lower lobe of lung
- lactiferous duct
- pons
- inferior ganglion of vagus nerve
- pylorus
- renal medulla
- retinal pigment epithelium
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| Top expressed in | - ureter
- ganglionic eminence
- jejunum
- cerebellum
- cerebellar cortex
- colon
- duodenum
- superior frontal gyrus
- renal cortex
- liver
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- protein homodimerization activity
- identical protein binding
- kinase activity
- MAP kinase kinase kinase activity
- protein serine/threonine kinase activity
- protein kinase activity
- ATP binding
- protein kinase binding
- metal ion binding
- nucleotide binding
- transferase activity
- JUN kinase kinase kinase activity
- IkappaB kinase complex binding
- enzyme binding
| Cellular component | - membrane
- cytoplasm
- IkappaB kinase complex
| Biological process | - phosphorylation
- JNK cascade
- protein phosphorylation
- protein autophosphorylation
- positive regulation of NF-kappaB transcription factor activity
- MAPK cascade
- positive regulation of neuron maturation
- peptidyl-serine phosphorylation
- positive regulation of axon extension
- positive regulation of neuron projection arborization
- positive regulation of branching morphogenesis of a nerve
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001242314 NM_001242317 NM_004721 |
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RefSeq (protein) | |
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NP_001229243 NP_001229246 NP_004712 |
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Location (UCSC) | Chr 3: 185.28 – 185.49 Mb | Chr 16: 21.61 – 21.75 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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