Interleukin-22 receptor

interleukin 22 receptor, alpha 1
Identifiers
SymbolIL22RA1
Alt. symbolsIL22R
NCBI gene58985
HGNC13700
OMIM605457
RefSeqNM_021258
UniProtA8K839
Other data
LocusChr. 1 p36.11
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StructuresSwiss-model
DomainsInterPro
interleukin 22 receptor, alpha 2
Identifiers
SymbolIL22RA2
NCBI gene116379
HGNC14901
OMIM606648
RefSeqNM_181310
UniProtQ969J5
Other data
LocusChr. 6 q24.1-24.2
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StructuresSwiss-model
DomainsInterPro

Interleukin-22 receptor is a type II cytokine receptor. It binds to Interleukin-22. It is a heterodimer of α1[1] and IL-10Rβ2[1] subunits.

References

  1. ^ a b Xie MH, Aggarwal S, Ho WH, Foster J, Zhang Z, Stinson J, Wood WI, Goddard AD, Gurney AL (2000). "Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R". J. Biol. Chem. 275 (40): 31335–9. doi:10.1074/jbc.M005304200. PMID 10875937.

External links

  • Receptors,+Interleukin-22 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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Cytokine receptors
Chemokine receptor
(GPCRs)
CC
CXC
Other
TNF receptor
1-10
11-20
21-27
JAK-STAT
Type I
γ-chain
β-chain
gp130
IL12RB1
Other
Type II
Ig superfamilyIL 17 familyEnzyme-linked receptor
  • v
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IL-1
IL-2
IL-3
IL-4
IL-5
  • Antagonists: YM-90709
  • Antisense oligonucleotides: TPI ASM8
IL-6
IL-7
IL-8
  • See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead.
IL-9
  • Antibodies: Enokizumab
IL-10
IL-11
IL-12
IL-13
IL-15
IL-17
IL-18
IL-20
IL-21
  • Antibodies: NNC0114-0005
  • NNC0114-0006
IL-22
IL-23
IL-27
IL-28
IL-31
IL1RL1
IL1RL2
Others
JAK
  • See here instead.
Others


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