Символи | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153, DNA damage-inducible transcript 3, DNA damage inducible transcript 3, C/EBPzeta, AltDDIT3 |
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Онтологія гена |
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Молекулярна функція | • DNA binding • cAMP response element binding protein binding • GO:0001106 transcription corepressor activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • transcription factor binding • GO:0000975 transcription cis-regulatory region binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • leucine zipper domain binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • protein homodimerization activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific |
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Клітинна компонента | • цитоплазма • гіалоплазма • late endosome • CHOP-C/EBP complex • нуклеоплазма • transcription factor AP-1 complex • protein-DNA complex • CHOP-ATF4 complex • CHOP-ATF3 complex • клітинне ядро |
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Біологічний процес | • GO:0097285 апоптоз • release of sequestered calcium ion into cytosol • negative regulation of protein kinase B signaling • negative regulation of fat cell differentiation • negative regulation of myoblast differentiation • GO:0009373 regulation of transcription, DNA-templated • positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway • positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress • negative regulation of DNA binding • mRNA transcription by RNA polymerase II • positive regulation of neuron death • GO:1901227 negative regulation of transcription by RNA polymerase II • Wnt signaling pathway • cell redox homeostasis • response to endoplasmic reticulum stress • PERK-mediated unfolded protein response • ER overload response • cellular response to DNA damage stimulus • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • ATF6-mediated unfolded protein response • positive regulation of neuron apoptotic process • response to unfolded protein • intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress • negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding • positive regulation of interleukin-8 production • response to starvation • negative regulation of determination of dorsal identity • клітинний цикл • regulation of DNA-templated transcription in response to stress • GO:0045996 negative regulation of transcription, DNA-templated • negative regulation of canonical Wnt signaling pathway • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • proteasome-mediated ubiquitin-dependent protein catabolic process • blood vessel maturation • negative regulation of CREB transcription factor activity • Відповідь на незгорнуті білки • establishment of protein localization to mitochondrion • intrinsic apoptotic signaling pathway in response to nitrosative stress • negative regulation of DNA-binding transcription factor activity • positive regulation of DNA-binding transcription factor activity • protein complex oligomerization • negative regulation of cold-induced thermogenesis • regulation of autophagy • positive regulation of intrinsic apoptotic signaling pathway |
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Джерела:Amigo / QuickGO | |