| Наявні структури |
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| PDB | Пошук ортологів: PDBe RCSB |
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| Список кодів PDB | | 1KHU, 2LAW, 2LAX, 2LAY, 2LAZ, 2LB0, 2LB1, 3Q47, 3Q4A | | |
| Онтологія гена |
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| Молекулярна функція | • DNA binding
• co-SMAD binding
• protein homodimerization activity
• I-SMAD binding
• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
• зв'язування з іоном металу
• GO:0001948, GO:0016582 protein binding
• identical protein binding
• protein heterodimerization activity
• protein kinase binding
• sequence-specific DNA binding
• DEAD/H-box RNA helicase binding
• primary miRNA binding
• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
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| Клітинна компонента | • цитоплазма
• integral component of membrane
• SMAD protein complex
• гіалоплазма
• transcription regulator complex
• внутрішньоклітинний
• нуклеоплазма
• nuclear inner membrane
• клітинне ядро
• GO:0009327 protein-containing complex
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| Біологічний процес | • GO:0007329 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
• SMAD protein complex assembly
• ureteric bud development
• GO:0009373 regulation of transcription, DNA-templated
• SMAD protein signal transduction
• embryonic pattern specification
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
• GO:1904579 cellular response to organic cyclic compound
• hindbrain development
• cellular response to BMP stimulus
• cardiac muscle cell proliferation
• BMP signaling pathway
• transcription, DNA-templated
• MAPK cascade
• protein phosphorylation
• gamete generation
• cartilage development
• GO:1901313 positive regulation of gene expression
• positive regulation of osteoblast differentiation
• positive regulation of cartilage development
• GO:1990744, GO:1990729 primary miRNA processing
• mesodermal cell fate commitment
• inflammatory response
• bone development
• transforming growth factor beta receptor signaling pathway
• midbrain development
• GO:0072468 сигнальна трансдукція
• negative regulation of cell population proliferation
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• osteoblast fate commitment
• homeostatic process
• transcription by RNA polymerase II
• positive regulation of pri-miRNA transcription by RNA polymerase II
• protein deubiquitination
• positive regulation of sprouting angiogenesis
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| Джерела:Amigo / QuickGO | |
