Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 4KV4, 1NFI, 2LSP, 2O61, 3GUT, 3QXY, 3RC0, 4KV1, 2N22 | | |
Онтологія гена |
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Молекулярна функція | • protein N-terminus binding • ankyrin repeat binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • histone deacetylase binding • enzyme binding • phosphate ion binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • protein homodimerization activity • chromatin binding • NF-kappaB binding • GO:0001948, GO:0016582 protein binding • protein kinase binding • DNA binding • sequence-specific DNA binding • actinin binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • chromatin DNA binding • ubiquitin protein ligase binding • GO:0000983 RNA polymerase II general transcription initiation factor activity • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • identical protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • transcription factor binding • GO:0032403 protein-containing complex binding |
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Клітинна компонента | • цитоплазма • гіалоплазма • I-kappaB/NF-kappaB complex • transcription regulator complex • NF-kappaB complex • нуклеоплазма • клітинне ядро • ядерце • NF-kappaB p50/p65 complex • GO:0009327 protein-containing complex • синапс • glutamatergic synapse |
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Біологічний процес | • response to amino acid • response to interleukin-1 • cellular response to interleukin-6 • response to progesterone • response to organic substance • Fc-epsilon receptor signaling pathway • GO:1903105 negative regulation of insulin receptor signaling pathway • defense response to virus • positive regulation of chondrocyte differentiation • animal organ morphogenesis • response to muscle stretch • response to cytokine • GO:1903363 negative regulation of protein catabolic process • cytokine-mediated signaling pathway • negative regulation of extrinsic apoptotic signaling pathway • response to mechanical stimulus • response to muramyl dipeptide • stimulatory C-type lectin receptor signaling pathway • transcription, DNA-templated • response to insulin • negative regulation of NIK/NF-kappaB signaling • nucleotide-binding oligomerization domain containing 2 signaling pathway • membrane protein intracellular domain proteolysis • inflammatory response • GO:0022415 viral process • response to cobalamin • hair follicle development • positive regulation of miRNA metabolic process • acetaldehyde metabolic process • cellular response to hepatocyte growth factor stimulus • cellular response to nicotine • negative regulation of apoptotic process • cellular defense response • response to morphine • response to lipopolysaccharide • cellular response to interleukin-1 • response to inorganic substance • regulation of inflammatory response • response to cAMP • GO:0045996 negative regulation of transcription, DNA-templated • response to hydrogen peroxide • positive regulation of Schwann cell differentiation • defense response • response to bacterium • GO:1904578 response to organic cyclic compound • GO:0010260 старіння людини • positive regulation of cell population proliferation • positive regulation of I-kappaB kinase/NF-kappaB signaling • liver development • response to UV-B • T cell receptor signaling pathway • cellular response to lipopolysaccharide • positive regulation of type I interferon production • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • cellular response to hydrogen peroxide • GO:0009373 regulation of transcription, DNA-templated • tumor necrosis factor-mediated signaling pathway • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • positive regulation of T cell receptor signaling pathway • positive regulation of NF-kappaB transcription factor activity • cellular response to peptidoglycan • cellular response to tumor necrosis factor • regulation of NIK/NF-kappaB signaling • positive regulation of NIK/NF-kappaB signaling • GO:0007329 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus • positive regulation of pri-miRNA transcription by RNA polymerase II • regulation of DNA-templated transcription in response to stress • cellular response to lipoteichoic acid • GO:1901227 negative regulation of transcription by RNA polymerase II • negative regulation of protein sumoylation • pri-miRNA transcription by RNA polymerase II • cellular response to angiotensin • interleukin-1-mediated signaling pathway • cellular response to vascular endothelial growth factor stimulus • negative regulation of pri-miRNA transcription by RNA polymerase II • postsynapse to nucleus signaling pathway • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization • I-kappaB kinase/NF-kappaB signaling • NIK/NF-kappaB signaling • positive regulation of leukocyte adhesion to vascular endothelial cell |
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Джерела:Amigo / QuickGO | |