| ETS1 |
|---|
 |
| Наявні структури |
|---|
| PDB | Пошук ортологів: PDBe RCSB |
|---|
| Список кодів PDB | | 1GVJ, 2NNY, 2STT, 2STW, 3MFK, 3RI4, 3WTS, 3WTT, 3WTU, 3WTV, 3WTW, 3WTX, 3WTY, 3WTZ, 3WU0, 3WU1, 4L0Y, 4L0Z, 4L18, 4LG0 | | |
| Ідентифікатори |
|---|
| Символи | ETS1, ETS-1, EWSR2, p54, c-ets-1, ETS proto-oncogene 1, transcription factor |
|---|
| Зовнішні ІД | OMIM: 164720 MGI: 95455 HomoloGene: 3837 GeneCards: ETS1 |
|---|
| |
| Пов'язані генетичні захворювання |
|---|
| ожиріння, целіакія, системний червоний вовчак[1] |
| Онтологія гена |
|---|
| Молекулярна функція | • DNA binding
• sequence-specific DNA binding
• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• transcription factor binding
• GO:0001948, GO:0016582 protein binding
• identical protein binding
• transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
• GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
• sequence-specific double-stranded DNA binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
• histone acetyltransferase binding
|
|---|
| Клітинна компонента | • цитоплазма
• transcription regulator complex
• нуклеоплазма
• клітинне ядро
|
|---|
| Біологічний процес | • regulation of apoptotic process
• pituitary gland development
• response to estradiol
• response to interleukin-1
• response to hypoxia
• GO:0009373 regulation of transcription, DNA-templated
• positive regulation of erythrocyte differentiation
• cell motility
• еструс
• процес імунної системи
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
• GO:1904576 response to antibiotic
• жіноча вагітність
• angiogenesis involved in wound healing
• positive regulation of cell migration
• response to mechanical stimulus
• response to laminar fluid shear stress
• negative regulation of cell cycle
• regulation of angiogenesis
• transcription by RNA polymerase II
• regulation of extracellular matrix disassembly
• transcription, DNA-templated
• positive regulation of endothelial cell migration
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• PML body organization
• response to wounding
• GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь
• positive regulation of cell population proliferation
• hypothalamus development
• negative regulation of inflammatory response
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• negative regulation of cell population proliferation
• cellular response to hydrogen peroxide
• positive regulation of inflammatory response
• pri-miRNA transcription by RNA polymerase II
• positive regulation of leukocyte adhesion to vascular endothelial cell
• GO:1901313 positive regulation of gene expression
• positive regulation of blood vessel endothelial cell migration
• positive regulation of angiogenesis
• диференціація клітин
|
|---|
| Джерела:Amigo / QuickGO | |
| Шаблон експресії |
|---|
 |
| Більше даних |
| Ортологи |
|---|
| Види | Людина | Миша |
|---|
| Entrez | | |
|---|
| Ensembl | | |
|---|
| UniProt | | |
|---|
| RefSeq (мРНК) | | NM_001143820
NM_001162422
NM_005238
NM_001330451 |
| |
|---|
| RefSeq (білок) | | NP_001137292
NP_001155894
NP_001317380
NP_005229 |
| NP_001033731
NP_035938
NP_001359463
NP_001359464
NP_001359465
| | NP_001359466 |
|
|---|
| Локус (UCSC) | Хр. 11: 128.46 – 128.59 Mb | Хр. 9: 32.64 – 32.76 Mb |
|---|
| PubMed search | [2] | [3] |
|---|
| Вікідані |
| Див./Ред. для людей | Див./Ред. для мишей |
|
